About Mary Jane's Botanicals
A Legacy of Whole-Plant Healing with Hemp-Infused CBD Products
At Mary Jane’s Botanicals, our journey began with a simple mission: to create natural CBD products that support healing, wellness, and balance—without compromising on purity or sustainability. Founded as a sister brand to Mary Jane’s Medicinals, one of the original pioneers in cannabis-infused topicals, we’ve carried forward that same commitment to whole-plant infusion and organic ingredients into the world of hemp.
We believe in the power of the entourage effect—that cannabinoids, terpenes, and plant compounds work best together, just as nature intended. That’s why we use full-spectrum hemp oil and a gentle infusion process to retain the complete therapeutic profile of the plant.
Each product we create is made in small batches with care, using only organic Colorado-grown hemp, rich plant-based oils, and therapeutic essential oils. From CBD salves and bath bombs to tinctures and massage oils, our formulations are simple, effective, and earth-conscious.
Driven by respect for nature and a deep understanding of herbal healing, we invite you to discover a better way to feel good—naturally.
Our Whole-Plant CBD Philosophy
At Mary Jane’s Botanicals, we believe in honoring the natural synergy found in the hemp plant. Backed by thousands of years of plant evolution and healing tradition, hemp contains a powerful spectrum of beneficial compounds that are most effective when kept intact. That’s why we follow a whole-plant approach—preserving the cannabinoids, terpenes, flavonoids, and other naturally occurring phytochemicals to create more holistic, effective CBD products.
Unlike many brands that rely on isolated extracts or solvent-based extractions, we use a gentle infusion process that retains the full range of therapeutic compounds found in organically grown hemp. This results in full-spectrum CBD oil that supports the body’s natural systems more completely than isolated cannabinoids alone.
When these compounds work together, they amplify each other’s effects—a powerful synergy known as the Entourage Effect. This is the foundation of our product line: real, plant-based healing that respects the wisdom of the whole plant.
Our hemp-infused products are made with care, passion, and a deep respect for herbal medicine. By combining full-spectrum hemp with carefully selected medicinal herbs and nourishing botanical oils, we create natural wellness solutions that are greater than the sum of their parts.
The Science Behind How Our CBD Products Work
Understanding the Endocannabinoid System (ECS)
At the core of our product philosophy is the science of the Endocannabinoid System (ECS)—a complex network of neurotransmitters and receptors found throughout the human body. The ECS plays a vital role in maintaining homeostasis, or internal balance, and is located in the brain, nervous system, immune system, skin, connective tissues, and many major organs.
Your body naturally produces endocannabinoids, which bind to ECS receptors to help regulate critical functions like stress response, pain perception, mood, sleep, inflammation, immune function, appetite, motivation, and more. This system is essential for physical and emotional well-being—so essential, in fact, that you literally can’t live without it.
Phyto-Cannabinoids and CBD from Hemp
Our CBD topicals and tinctures are made with hemp-derived phyto-cannabinoids—plant-based compounds that closely resemble the endocannabinoids your body naturally produces. These include familiar cannabinoids such as CBD (cannabidiol), CBN (cannabinol), and CBG, among over 100 others already identified in the hemp plant.
When applied topically or taken internally, phyto-cannabinoids interact with the ECS by binding to its receptors, helping your body return to a state of balance. This is why CBD is known to support relief from pain, inflammation, anxiety, and more—it’s working with your body’s own built-in systems of regulation and healing.
At Mary Jane’s Botanicals, we believe in enhancing the body’s natural capacity to heal and restore itself. That’s why our products are crafted to support the ECS, allowing your body to do what it was designed to do: thrive.